GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | trans | rs7122488 | 1 | rs6483800 | chr11:21846130 | AKR7L | chr1:19592476-19600568:- | -0.32 | -5.94 | 5.64E-9 | Attention function in attention deficit hyperactive disorder |
| THCA | trans | rs6600671 | 1 | rs6600669 | chr1:121213639 | NBPF14 | chr1:148003643-148346791:- | 0.44 | 10.35 | 8.97E-23 | Hip geometry |
| THCA | trans | rs6600671 | 1 | rs6600671 | chr1:121200490 | NBPF14 | chr1:148003643-148346791:- | -0.38 | -8.42 | 4.58E-16 | Hip geometry |
| THCA | trans | rs853679 | 1 | rs68141011 | chr6:28217797 | BTN3A2 | chr6:26365398-26378546:+ | -0.54 | -10.42 | 4.69E-23 | Depression |
| THCA | trans | rs10037055 | 1 | rs6886255 | chr5:176718361 | LOC388955 | chr2:63849182-63850159:- | 0.73 | 19.01 | 1.94E-60 | Migraine without aura |
| THCA | trans | rs853679 | 1 | rs6901575 | chr6:28250984 | BTN3A2 | chr6:26365398-26378546:+ | -0.5 | -9.8 | 9.06E-21 | Depression |
| THCA | trans | rs1056667 | 1 | rs6903973 | chr6:26499942 | ZNF322B | chr9:99957633-99961910:- | 0.54 | 10.2 | 3.09E-22 | Educational attainment |
| THCA | trans | rs853679 | 1 | rs6905391 | chr6:28262686 | BTN3A2 | chr6:26365398-26378546:+ | -0.47 | -9.24 | 7.9E-19 | Depression |
| THCA | trans | rs1056667 | 1 | rs6910899 | chr6:26524339 | ZNF322B | chr9:99957633-99961910:- | 0.54 | 10.3 | 1.35E-22 | Educational attainment |
| THCA | trans | rs1056667 | 1 | rs6922824 | chr6:26553815 | ZNF322B | chr9:99957633-99961910:- | -0.57 | -11.06 | 1.79E-25 | Educational attainment |
| THCA | trans | rs1056667 | 1 | rs6924838 | chr6:26571756 | ZNF322B | chr9:99957633-99961910:- | 0.59 | 11.32 | 1.79E-26 | Educational attainment |
| THCA | trans | rs1056667 | 1 | rs6925703 | chr6:26521589 | ZNF322B | chr9:99957633-99961910:- | 0.54 | 10.3 | 1.35E-22 | Educational attainment |
| THCA | trans | rs1056667 | 1 | rs6925895 | chr6:26572165 | ZNF322B | chr9:99957633-99961910:- | 0.59 | 11.32 | 1.79E-26 | Educational attainment |
| THCA | trans | rs1056667 | 1 | rs6926629 | chr6:26499903 | ZNF322B | chr9:99957633-99961910:- | 0.54 | 10.2 | 3.09E-22 | Educational attainment |
| THCA | trans | rs1056667 | 1 | rs6930120 | chr6:26555484 | ZNF322B | chr9:99957633-99961910:- | 0.57 | 11.04 | 2.09E-25 | Educational attainment |